Stereochemistry

Pharmaceutical (Stereochemistry) - Enantiomers have different effect on human bodies - One enantiomer is more effective than the other - One enantiomer is useful, while the other causes harm Particular significance is given to stereochemistry in the pharmaceutical sector. This is seen by the different results that enantiomerism in pharmacological goods yields. 1. Enantiomers that have different effects on the human body Let's start by examining propoxyphene. The human body reacts differently to the two enantiomers, dextropropoxyphene and levopropoxyphene, since they are specific to distinct receptors. Darvon, or dextropropoxyphene, is a medication used to relieve pain that is marketed as an analgesic. On the other hand, levopropoxyphene which was originally sold as Novrad has a different pharmocological impact. It relieves coughing by acting as an antitussive.  Methorphan's enantiomers also exhibit diverse toxicological and pharmacological properties. Since dextromethorphan int

https://youtu.be/dGyM4l_sSgQ?si=tn79S2wUd1Znnmgq Stereochemistry is a compound that contains the same compound number but different orientation and arrangement in 3D Even though it might look the same, each of the compound delivers different type of function  These mirror images of compound are called a pair of enantiomers,. When one of the enantiomers are rotated, it will show a different structure of the same compound. A carbon that consisted of 4 different types of substituents are called as chirality centres.

 

Enantiomers are important on deciding the perfect and most effective drugs, as shown in the picture above, (a) fits the receptor site while (b) doesn't fit the receptor site. This helps with mass production of more effective drugs Drugs are proven simpler to create and thus creates less interactions which helps enhance effectiveness.  various enantiomeric medications have various effects on the human body; one may alleviate a symptom while the other may have the opposite effect. Conventional methods are unable to produce the chiral environment necessary for the separation of pairs of enantiomers, which causes a structural imbalance.